Understanding Hughes Syndrome: Case Studies for Patients by Graham R.V. Hughes MD, FRCP (auth.), Graham R. V. Hughes

Understanding Hughes Syndrome: Case Studies for Patients by Graham R.V. Hughes MD, FRCP (auth.), Graham R. V. Hughes

By Graham R.V. Hughes MD, FRCP (auth.), Graham R. V. Hughes (eds.)

Besides AIDS, antiphospholipid syndrome used to be the foremost clinical discovery of the past due twentieth century, so for lots of it's nonetheless deemed a ‘new’ disorder. the invention of ‘sticky blood’ (commonly often called antiphospholipid syndrome or ‘Hughes Syndrome’) got here out of years of remark of sufferers who had built lupus. Many experts within the Nineteen Seventies have been drawn to the neurological elements of lupus, and Dr Hughes, between others, spent a couple of years learning the mechanisms of mind irritation. within the mid Seventies, Hughes saw a few younger ladies with a kind of viral paralysis, the place curiously lots of them carried an antibody of their blood really directed opposed to ‘phospholipid’ – one of many parts of mind and spinal twine. It quick turned obvious that people who had "anti-phospholipid antibodies" suffered from a bent not just to increase mind and spinal wire signs, but additionally a bent to advance either vein and artery thrombosis. As research persevered it grew to become obvious that those indicators weren't simply constrained to lupus sufferers, yet happened in others too, particularly people with serious migraines, with repeated strokes, with reminiscence loss, and in girls with recurrent miscarriage.

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Sample text

On arrival at Heathrow airport, she made her way off the plane at the usual snail’s pace with the rest of the passengers. As she walked up the connecting gangway into the airport, she felt giddy, suddenly unwell and short of breath. She managed to hold on to a pillar, but then collapsed. She was taken to the medical centre at the airport and transferred to hospital as an emergency. The diagnosis was, in fact, a “pulmonary embolism” – a lung blood clot. Although there was no clear proof, it was suspected that the clot had arisen in one of the leg or pelvic veins and traveled onto the lung.

Take Home Message Spontaneous metatarsal fracture – “march fracture” – is a bizarre, yet not uncommon condition. The world of orthopedics is recognizing that in some cases of unexpected bone fracture, a clotting disorder such as Hughes syndrome can be responsible.

Take Home Message Spontaneous metatarsal fracture – “march fracture” – is a bizarre, yet not uncommon condition. The world of orthopedics is recognizing that in some cases of unexpected bone fracture, a clotting disorder such as Hughes syndrome can be responsible.

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