[Magazine] Scientific American. Vol. 273. No 6

[Magazine] Scientific American. Vol. 273. No 6

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Additional info for [Magazine] Scientific American. Vol. 273. No 6

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M. J. Welsh, L. C. Tsui, T. F. Boat and A. L. Beaudet in Metabolic and Molecular Basis of Inherited Disease. Edited by C. R. Scriver, A. L. Beaudet, W. S. Sly and D. Valle. McGraw-Hill, 1994. Copyright 1995 Scientific American, Inc. SCIENTIFIC AMERICAN December 1995 59 SCIENCE IN PICTURES The Leaning Tower of Pisa The famous tower has been tilting since the 12th century. Now engineers are using 20th-century technology in hopes of saving the ancient landmark by Paolo Heiniger Copyright 1995 Scientific American, Inc.

Investigators wonder as well whether the CFTR protein has functions beyond its role as a chloride channel. Among the possibilities being considered is that CFTR may help regulate chloride channels distinct from CFTR. Researchers have also posited that the molecule may indirectly alter the mix of sugars on the epithelial surface in ways that favor colonization by certain bacteria. the residual activity can make for somewhat less severe symptoms. These patterns do not always hold, however, and so making predictions in individual cases remains problematic.

Shortly thereafter the tower at Pisa was closed to visitors. In 1990 a special commission, composed of Italian and foreign experts in the Þelds of structural engineering, geotechnical engineering, history of art and restoration of monuments, was brought together by the Italian government to determine new ways to save the tower. The group I work with, the Consorzio Progetto Torre di Pisa (the Tower of Pisa Project Consortium), has supervised several projects that have stabilized the structure and slowed the rate of its incline.

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